Genetic control of immune cell proliferation
Germinal centers are transient structures in the lymph nodes where antibody-producing B cells proliferate and differentiate at extraordinary rates. Germinal centers can be visually divided into a dark zone and light zone. For the proliferation and differentiation to occur, B cells must cycle between the two zones. Investigators have discovered how specific genes regulate this cycling. The findings provide new insights on how certain types of lymphomas form. …read more
