What can zebrafish teach us about our survival in the face of mutations?
The CRISPR/Cas9 genome-editing tool reveals that sometimes an organism compensates for a mutation in a gene by changing how it regulates the expression of other related genes — a workaround of sorts. A good way to hunt out these kinds of genomic workarounds is to look at the RNA phase, which is the intermediary between gene and protein. …read more