Earthquake in the cell
Nuclear abnormalities such as nuclear blebs and micronuclei have devastating consequences for the genetic material and are associated with cancer or ageing. Scientists now revealed that the epigenetic enzyme MOF is crucial for the morphological integrity of the mammalian nucleus. Moreover, the study characterized the epigenetic landscape of nuclear abnormalities and discovered a formerly unknown epigenetic mechanism that seems to protect cells from additional damage. …read more
